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Chemoprotective effect of cysteamine against the induction of micronuclei by methyl methanesulfonate and cyclophosphamide Genet. Mol. Biol.
Santos-Mello,Renato; Deimling,Luiz Irineu; Lauer Júnior,Claudio; Carvalho,Thaís Rieger de.
Cysteamine or 2-mercaptoethylamine (MEA) is an aminothiol with a well-known radioprotective action. No specific information is available in the literature about the possible chemoprotective action of MEA against genotoxic chemical agents. This paper presents the results of studies on the ability of MEA to protect mouse bone marrow polychromatic erythrocytes against the induction of micronuclei by alkylating agents such as methyl methanesulfonate (MMS) and cyclophosphamide (CP). We observed that MEA administered intraperitoneally 30 min before or 30 min after the administration of MMS or CP significantly reduced the frequency of micronucleated polychromatic erythrocytes (MNPCEs) induced by the alkylating agents. When MEA was administered in combination with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cysteamine; MEA; Micronuclei; Amifostine; WR-2721.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100027
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Selecting ecological indicators to compare maintenance costs related to the compensation of damaged ecosystem services ArchiMer
Vaissiere, Anne-charlotte; Levrel, Harold; Hily, Christian; Le Guyader, Damien.
The aim of this paper is to compare different maintenance costs of ecosystem service arising from a hypothetical case of environmental damage in order to help to understand how the different ecosystem services are considered in decision making processes. Compensatory measures are aimed precisely at maintaining the level of supply of ecosystem services. According to the literature, compensatory measures like restoration are usually applied to specific ecosystem services. We used the Millennium Ecosystem Assessment (MEA) categories of ecosystem service. For each MEA category, several ecological indicators are selected, and the cost of the compensatory measures required to fulfill the goal of no net loss is assessed using the Habitat Equivalency Analysis...
Tipo: Text Palavras-chave: Ecosystem services; Maintenance costs; Compensatory measures; HEA; MEA; No net loss.
Ano: 2013 URL: http://archimer.ifremer.fr/doc/00134/24552/22997.pdf
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Who Should Make the Rules of Trade? - The Complex Issue of Multilateral Environmental Agreements AgEcon
Kerr, William A..
In recent years, governments have negotiated a number of Multilateral Environmental Agreements (MEAs) that include clauses regarding trade measures that conflict with their WTO obligations. As yet, there has been no formal dispute regarding which obligations should prevail, but the threat of conflict is perceived to be sufficiently grave for the parties to the Doha Ministerial to agree to examine the issue. Those who have strong preferences for environmental amenities have put considerable effort into fostering MEAs and are lobbying hard for them to prevail over the WTO in their areas of competence. The current lack of transparency caused by conflicting rules increases the degree of risk perceived in the international commercial environment. As MEAs allow...
Tipo: Journal Article Palavras-chave: Doha; MEA; Negotiations; Ratification; Trade measures; WTO; International Relations/Trade.
Ano: 2002 URL: http://purl.umn.edu/23928
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